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Literature summary extracted from
- Versatile loops in mycocypins inhibit three protease families (2010), J. Biol. Chem., 285, 308-316.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.22.43 | expressed in Pichia pastoris | Homo sapiens |
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 3.4.22.43 | cathepsin V in complex with clitocypin, vapor diffusion method, using 0.4 M Li2SO4, 12% (w/v) polyethylene glycol 800, 20% (v/v) glycerol | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.43 | clitocypin | - |
Homo sapiens | |
| 3.4.22.43 | macrocypin-1 | - |
Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.43 | Homo sapiens | O60911 | - |
- |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.22.43 | 0.00000008 | - |
clitocypin | pH and temperature not specified in the publication | Homo sapiens | |
| 3.4.22.43 | 0.00000069 | - |
macrocypin-1 | pH and temperature not specified in the publication | Homo sapiens |
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Release 2023.1 (January 2023)
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